The majority of patients developing this condition are Black, but it may also occur in Caucasians and Hispanics. Tri-Luma Cream contains hydroquinone, which may produce exogenous ochronosis, a gradual blue-black darkening of the skin, the occurrence of which should prompt discontinuation of therapy. Allergic contact dermatitis may also occur. If anaphylaxis, asthma or other clinically significant hypersensitivity reactions occur, institute appropriate therapy and discontinue Tri-Luma. Tri-Luma Cream contains sodium metabisulfite, a sulfite that may cause allergic-type reactions including anaphylactic symptoms and life-threatening asthmatic episodes in susceptible individuals. Warnings and Precautions Hypersensitivity Tri-Luma Cream is contraindicated in individuals with a history of hypersensitivity to this product or any of its components. Related/similar drugs Triderma Dosage Forms and StrengthsĮach gram of Tri-Luma Cream contains 0.1 mg of fluocinolone acetonide, 40 mg of hydroquinone, and 0.5 mg of tretinoin in a light yellow, hydrophilic cream base. It is not for oral, ophthalmic, or intravaginal use. Patients may use moisturizers and/or cosmetics during the day. Therapy should be discontinued when control is achieved.ĭuring the day, use a sunscreen of SPF 30, and wear protective clothing. ![]() ![]() Apply Tri-Luma Cream to the hyperpigmented areas of melasma including about 1/2 inch of normal appearing skin surrounding each lesion. Gently wash the face and neck with a mild cleanser. Tri-Luma Dosage and AdministrationĪpply a thin film of Tri-Luma Cream to the effected area once daily, at least 30 minutes before bedtime. The safety and efficacy of Tri-Luma Cream in the treatment of hyperpigmentation conditions other than melasma of the face have not been studied.īecause pregnant and lactating women were excluded from, and women of childbearing potential had to use birth control measures in the clinical trials, the safety and efficacy of Tri-Luma Cream in pregnant women and nursing mothers have not been established. Excessive bleaching resulting in undesirable cosmetic effect in patients with darker skin cannot be excluded. The safety and efficacy of Tri-Luma Cream in patients of Fitzpatrick Skin Types V and VI have not been studied. Melasma usually recurs upon discontinuation of Tri-Luma Cream. After achieving control with Tri-Luma Cream, some patients may be managed with other treatments instead of triple therapy with Tri-Luma Cream. Tri-Luma Cream is NOT indicated for the maintenance treatment of melasma. Tri-Luma Cream is a combination of fluocinolone acetonide (a corticosteroid), hydroquinone (a melanin synthesis inhibitor), and tretinoin (a retinoid) that is indicated for the short-term treatment of moderate to severe melasma of the face, in the presence of measures for sun avoidance, including the use of sunscreens. Expand Indications and Usage for Tri-Luma Indication The cream bleaches your skin in spots on the surface so it takes more makeup to cover and even out. Keep in mind I paid them to do this to my face basically. Well it wouldn't heal so I go back very upset nothing wrong with face before these peels I'm 35 never really had face issues et so the dermatologist says it caused my pigmentation to reverse causing the dark spots and prescribed me tri luma it was 280$ plus I will have to use special sunblock the rest of my life. The second one 60 percent burned a little nothing bad 2 weeks later my face was getting worse like severe burns I'm already medium dark skin. The first one was 40 percent which I did and it was fine. ![]() ![]() "So my story is a little different I went to the dermatologist to have a tiny mole cut off my eyebrow which was not even noticeable the girls working there were running a special on a lunch time chemical face peel so I nicely bought one package that came with 3 peels.
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